Panormou - 40, Ampelokipoi, Athens, Zip Code 11523

Panormou - 40
Ampelokipoi, Athens

+30 210 6983222 | +30 213 0312000

Pregnancy Screening Thrombophylia inhereted

GENOVAL ANALYSIS OF THROMBOFILIA – NEOCREEN TESTING
WHAT IS

Genetic Thrombophilia is characterized by the condition in which the gene type (inherited) gives the tendency to form clots at any random point in the body.

 

BASIC APPEARANCES – INDICATIONS – IMPORTANCE

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Genetic testing is recommended for individuals who have:

  • personal or family history of thrombosis – cerebral infarctions – pulmonary embolism (parents – siblings)
  • influenced simple intravascular inflammatory – coagulation analytes (eg high homocysteine, fibrinogen, D-Dimmer)
  • multiple cardiovascular risk factors (smoking, hypertension, dyslipidemia, diabetes, obesity, diagnosed atherosclerosis, high inflammation markers, etc.)
  • contraceptive’s therapy (especially for smokers).

 

Especially in pregnancy, screeinig tests are recommended in:

  • high risk pregnancies (older, extracorporeal or twin)
  • unexplained – undiagnosed pregnancy abortions – cases of preeclampsia
  • women with relatives with thrombosis or unexplained miscarriages.

 

Undesirable cases of thrombophilia can lead to:

  • formation of a thrombus with the risk to be detached and cause a cardiovascular episode
  • a serious or even fatal cardiovascular event (ischemic stroke or heart attack, or pulmonary embolism, etc.)
  • gestational abortions from thrombosis in the developing placental vessels

 

The results of gene testing determine whether it is necessaryor not to:

  • adjust diet
  • undergo a  chronic vitamin supplement prophylactic therapy
  • administrate a drug prophylactic therapy (e.g. salospir, sintrom etc)
  • administrate a specific heparin based anticoagulant, during pregnancy

 

LABORATORY HEMATOLOGICAL TESTING

In the genomic analysis of thrombophilia,  a set of individual genes are analyzed.

The main test sets we propose are:

 

CVD-4 IVD  is the basic thrombophilic gene analysis kit, which includes the following genes:

  • Factor V Leiden (1619Α)
  • Prothrombin (G20210A)
  • MHTFR (C677T)
  • β-fibrinogen (-455G / A)

 

CVD-20 Research  is the complete gene analysis package for mutations or polymorphisms, and is recommended for pregnant women and those with a personal or family history of thrombophilia. The genes included are:

  • Factor V Leiden (G1601A)
  • HR2 (H1299R)
  • MTHFR (C677T)
  • MTHFR (A1298C)
  • PROTHROMBIN (G20210A)
  • β-fibrinogen (-455G / A)
  • FXIII (V34L)
  • PAI-1 (-675 4G/5G)
  • PAI-1 (-844G / A)
  • GPIIIa
  • APOB
  • ACE
  • GPIa(C807T)
  • APOE2/Ε3/Ε4*
  • PAI-2 (Ser413Cys)
  • eNOS G298A
  • EPCRH3 (A4600G)
  • EPCRH1 (G4678C)
  • LPA (A5673G)

 

Caution

It is always important to consult a qualified health professional before doing any genetic testing to make sure you fully understand the conditions being tested and the explanation of the results

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Information selected from :

  •  MayoClinic.org
  • Labtestsonline.org
  • Neoscreen Laboratories

The exact choice of tests required, is under the responsibility of your treating physician

Editor: I. Gratsias  Lab Director / Clinical Biochemist

Last Update May 2019

 

 

INFORMATION ON LABORATORY CONTROL
PREPARATION

Laboratory testing requires simple blood sampling. No preparation or diet is required, and the blood can be taken at any time of the day

Blood sampling can take place at any time of the day (laboratory hours from 7.30am to 7.30pm).

Samples (2x 2.5 ml EDTA tubes) can also be delivered worldwide, with special packages 

TIME OF DELIVERY OF RESULTS

The results are given

  • CVD-4 IVD : 5 -7 working days.
  • CVD-20 Research : 12 business days
CHARGES

Private costs for packages are:

  • CVD-4 -IVD : 120 euros.
  • CVD – 20 Research : from the initial price of 230 euros at a bid price to 180 euros

Medical Center Laboratories – Ultrasound Imaging – Doctors – Nursing – Health Services

24h/365d Medical Laboratory – Gene Analysis –

Clinical Doctors Cardiologist – Urologist
Directors I. Gratsias, I. Katsavochristos