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Prenatal testing analyzes blood parameters for possible diseases and infections in the future mother, which can endanger her or her pregnancy, and is also checked the health of the child to be born.
A prenatal check-up is aimed at all women, as there are many asymptomatic conditions that can cause serious complications in pregnancy and in the fetus - a newborn baby.
The analysis is selected for the investigation
General blood: hematocrit, white blood cells, and platelets are checked. The expectant mother is checked for anemias, systemic infections, inflammations, and coagulation factor sufficiency.
Hemoglobin electrophoresis and sickle test: check for heterozygosity for b-thalassemia (stigmatism of Mediterranean anemia). In case of a positive result, further testing for the future father is absolutely necessary.
Blood group and rhesus: performed to determine if the mother will need special treatment during pregnancy. In case of negative rhesus, we proceed to perform indirect Coombs.
Fasting sugar (glu), Glycated hemoglobin (HbA1c): ensure the absence of diabetes, for the smooth and safe growth rate of the fetus. Possible high sugar levels and diabetes are combined with particularly large fetuses and increased risk of pregnancy - birth. Due to diabetes that can appear during pregnancy, doctors also recommend the sugar curve from the sixth month of pregnancy, in order to ensure the absence of transient - pseudo - diabetes of pregnancy.
TSH (thyroid-stimulating hormone), anti-TPO (anti-thyroid antibodies), and anti-TG (anti-thyroglobulin antibodies): control the regulation of thyroid function, which determines the overall metabolism of the body and affects the pregnancy. The check of antibodies also controls the possibility of autoimmune thyroiditis, which during pregnancy may threaten her safety.
Antibodies against toxoplasma (Toxo IgG/IgM): by measuring them we find possible old infection and immunity against toxoplasma (toxoplasma is mainly transmitted by the feces of infected cats, contaminated undercooked meat, contaminated vegetables that have not been cleared well and kitchen utensils from undercooked meats and contaminated water). In case of the absence of antibodies (negative result), it is necessary to re-check this test during pregnancy.
Antibodies against rubella (Rubella IgG/IgM): by measuring them, we establish a possible old infection and immunization against the rubella virus. Rubella is a mild infectious exanthematous disease that mainly affects children, who have not been vaccinated. In the absence of antibodies (negative result), it is necessary to re-check it during pregnancy.
Antibodies against cytomegalovirus (CMV IgG/IgM): CMV is a herpes virus that is transmitted mainly through the blood and with these tests we find out if there is an old infection and immunization in the mother. In the absence of antibodies, retesting during pregnancy is necessary.
VDRL: in recent years with the movement of populations, there has been an increase in cases of sexually transmitted syphilis. With this laboratory test, we check if there is a bacterial infection, so that the appropriate treatment can be given to the mother in time for the safety of the baby.
Hepatitis B, C, and AIDS, (HBsAg, anti-HCV, anti-HIV I/II): laboratory testing for these viruses is essential, as they can be asymptomatic even in an advanced stage of infection. Appropriate measures can protect the unborn child from infection and protect the mother in a timely and effective manner.
HSV II: herpes viruses are extremely common in the general population (1 in 4 people). Screening the mother for HSV is important because the appropriate treatment in the last trimester of pregnancy generally prevents transmission of HSV to the child at birth. Newborns with HSV infection can experience serious health complications.
Listeria: mainly transmitted by soft cheeses (brie & camembert and cheeses containing blue substances such as Danish Blue & Stilton), raw uncooked meat, poultry, and fish, as it survives in refrigerator temperatures. Although listeria infection is not very common, testing for possible infection is recommended for a safe pregnancy.
Vaginal cultures, urine test - cultures: they are done so that, if needed, appropriate treatments can be given in time and there are no complications due to infection during pregnancy. During pregnancy, it is known that the choice of available drugs for treatment is limited.
INFORMATION FOR LABORATORY CHECK
The laboratory test requires a simple blood draw, urine sample, and vaginal fluid collection.
No preparation or diet is required, except for a 2-hour fast before the blood draw.
The collection of urine is suggested to be with the first urination and at least 2 days after the end of menstruation
The vaginal sample is taken at least 2 days after the end of menstruation and after an appointment.
BLOOD COLLECTION – SAMPLING
Blood sampling can be done at any time of the day (laboratory hours 7.30 a.m. – 7.30 p.m.).
For vaginal cultures by appointment and after 10.00 am.
EXPECTED TIME FOR THE RESULTS
The results of the basic prenatal are given in 2-3 working days.
Basic prenatal check-up tests are prescribed at the EOPYY, with the participation of the examinee as defined by the referral (15%, unless otherwise stated)
Information selected - indicative with sources: Interpretation of Diagnostic Tests - J.Wallach and https://labtestsonline.org
The choice and explanation of the use of the analysis is the exclusive responsibility of your doctor
Edited by : Ioannis Grattisia Head of Laboratory / MSc Clinical Biochemistry - Molecular Biology
2022 - 2023
Diagnostic: Director Biochemist I. Gratsia - Biopathologist I. Katsavochristos / M. Kolokouri - Radiologist S. Alagiannis
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