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Histocompatibility Antigens HLA

HLA histocompatibility antigens are the gene regions that regulate the genetic identity on the surface of our cells. Based on this identity, the functioning of the immune system is regulated.

HLA gene regions are mainly tested for the compatibility or non-compatibility of transplants.

In daily life, however, they are examined for the investigation of pathological conditions of the immune system.

The most frequently analyzed areas and the corresponding associated diseases are:

  1. HLA B-27 : Reactive arthritis, ankylosing spondylopathy
  2. HLA DR2 : Systemic lupus erythematosus
  3. HLA DR3: Autoimmune hepatitis, diabetes type I, Sjogren's syndrome
  4. HLA DR4: Rheumatoid arthritis, diabetes type I
  5. HLA DQ2 – DQ8 : Predisposition to Celiac Disease

No preparation is required for the laboratory tests.

The cost for the laboratory testing is:

HLA B-27: 50 euros

HLA B (whole group): 125 euros

HLA DR: 125 euros

HLA DR B1: 125 euros

HLA DQ2 & DQ8: 125 euros

Information selected - indicative with sources: Interpretation of Diagnostic Tests - J.Wallach and

The choice and explanation of the use of the analysis is the exclusive responsibility of your doctor

Edited by : Ioannis Grattisia Head of Laboratory / MSc Clinical Biochemistry - Molecular Biology

2022 - 2023

Biopathology Diagnostic Laboratory | Microbiological | Molecular | DNA | Ultrasonic | EOPYY – Clinic

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