Cancer – Gene testing
The onset of cancer is the result of the accumulation of multiple mutations in the DNA of cells
During life, cells in most organs are renewed – they die and are replaced by new cells. When they are renewed, the DNA from the old cell is faithfully copied from the old cell to the new one.
Rarely, a mistake occurs during cell replication that causes a mutation. The mutant cell is most likely not to be viable. But some are viable, and then we have a new different mutant – neoplastic cell.
Accumulation of multiple mutations in the same cell can lead to the creation of a cancerous one.
The importance of knowing the mutations we bring from our parents is extremely important knowledge. It shows us whether we have built up a certain level of mutations that constitute an increased chance of developing cancer.
The utilisation of the results, if eventually found positive for mutations, is based on the more rigorous proportional and planned execution of targeted – individualised screening tests.
The aim is the early detection of possible precancerous or cancerous tissues.
Early detection and diagnosis enables the possibility of :
- avoiding surgery
- if surgery is ultimately required, minimising the extent – severity of the surgery or any treatment that follows
- the best possible prognostic data for cure or successful treatment
In this effort, we are involved in the analysis of 483 genes simultaneously that are involved in the most common cancers, such as
- breast – ovaries
- intestine – gastric – pancreas
- kidney
- protector
- thyroid – parathyroid
- melanoma
- retinoblasting
Selected information from sources:
- MayoClinic.org
- Labtestsonline.org
- Interpretation of Diagnostic Tests – J.Wallach
The personalization of the check-up takes into account multiple parameters of personal and family history.
Depending on the case, the selection of tests may require some that are not mentioned on this page.
The exact selection is the responsibility of your attending physician.
Edited by: Ioannis Gratsias, Lab Director / Clinical Biochemist
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Cancer Check Up
Cancer gene screening is an important procedure that aims to determine the risk of cancer by analysing the genetic parameters of the individual. This screening can provide important information about the possibility of developing cancer and can determine the appropriate preventive measurements or preventive treatments for the individual. This type of screening has redefined the approach of medicine to cancer, as it provides the opportunity for personalised prevention and treatment.
The Cancer Check Up involves the analysis of gene mutations that may be linked to cancer. These mutations can be inherited or arise during a person’s lifetime due to external factors, such as exposure to carcinogens or solar radiation. Detecting these genetic changes can help identify people who are likely to develop cancer in the future and provide important information for personalising treatment and prevention.
Cancer screening can be performed for many types of cancer, including breast cancer, lung cancer, colon cancer, prostate cancer and others. Genetic testing can detect various cancer-related mutations in these tissues and predict the risk of developing the disease. This allows doctors to better predict and manage cancer, offering personalised treatment and prevention.
Another important area of gene testing for cancer is the ability to predict response to different treatments. Genetic testing can predict which patients are more likely to respond to certain treatments and which may have resistance to certain drugs. This helps to avoid adverse reaction to treatment and to improve prediction of the treatment outcome.
Overall, cancer gene screening provides important information on the risk of cancer development, personalisation of prevention and treatment and prediction of response to treatment. This type of screening is an important tool in the fight against cancer and offers the possibility for more tailored and effective medical care.